Yintoni i-Embolic Microspheres?

Iimpawu zokusetyenziswa (Chaza)

IiMicrospheres ze-Emboliczenzelwe ukusetyenziselwa ukuthintela ukungasebenzi kakuhle kwemithambo yegazi (ii-AVM) kunye neethumba ezine-hypervascular tumors, kuquka nee-uterine fibroids.

 

Igama Eliqhelekileyo okanye Eliqhelekileyo: Udidi lwePolyvinyl Alcohol Embolic Microspheres

Igama: Isixhobo Sokubethelela Imithambo Yemithambo

Udidi: Iklasi yesiBini

Iphaneli: Intliziyo kunye neMithambo

 

Inkcazo yesixhobo

 

Ii-Embolic Microspheres zii-hydrogel microspheres ezinokucinezelwa ezinemilo eqhelekileyo, umphezulu ogudileyo, kunye nobukhulu obulinganisiweyo, ezenziwe ngenxa yokuguqulwa kweekhemikhali kwizinto ze-polyvinyl alcohol (PVA). Ii-Embolic Microspheres zenziwe yi-macromer ethathwe kwi-polyvinyl alcohol (PVA), kwaye ziyakwazi ukufudumala emanzini, azikwazi ukuxutywa, kwaye zifumaneka ngobukhulu obahlukeneyo. Isisombululo sokugcina sisisombululo se-sodium chloride esingu-0.9%. Umxholo wamanzi we-microsphere e-polymerized ngokupheleleyo yi-91% ~ 94%. Ii-Microspheres zinokunyamezela ukucinezelwa kwe-30%.

Ii-Embolic Microspheres zifumaneka zingenazintsholongwane kwaye zipakishwe kwiibhotile zeglasi ezivaliweyo.

Ii-Embolic Microspheres zenzelwe ukusetyenziselwa ukuqinisa imithambo yegazi emithanjeni (ii-AVM) kunye nee-hypervascular tumors, kuquka nee-uterine fibroids. Ngokuthintela ukuhanjiswa kwegazi kwindawo ekujoliswe kuyo, ithumba okanye i-malformation ayifumani izondlo kwaye iyancipha ngobukhulu.

Ii-Embolic Microspheres zinokuziswa ngee-microcatheters eziqhelekileyo kuluhlu lwe-1.7-4 Fr. Ngexesha lokusetyenziswa, ii-Embolic Microspheres zixutywa ne-arhente yokungafani engekhoyo ionic ukwenza isisombululo sokuxhoma. Ii-Embolic Microspheres zenzelwe ukusetyenziswa kube kanye kwaye zinikezelwa zingenazintsholongwane kwaye azina-pyrogenic. Ulwakhiwo lwesixhobo se-Embolic Microsphere luchazwe kwiTheyibhile 1 kunye neTheyibhile 2 ngezantsi.

Phakathi kobukhulu obahlukeneyo be-Embolic Microspheres, ubukhulu obunokusetyenziswa kwi-uterine fibroid embolization yi-500-700μm, 700-900μm kunye ne-900-1200μm.

Itheyibhile: Uqwalaselo lwezixhobo ze-Embolic Microspheres
Imveliso Ikhowudi	Ilinganisiwe Ubungakanani (µm)	Ubungakanani	Isalathisi
			Ii-Hypervascular Tumors/ I-Arteriovenous Iimpazamo	I-Fibroid yesibeleko
B107S103	100-300	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	No
B107S305	300-500	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	No
B107S507	500-700	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
B107S709	700-900	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
B107S912	900-1200	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
B207S103	100-300	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	No
B207S305	300-500	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	No
B207S507	500-700	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
B207S709	700-900	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
B207S912	900-1200	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe

 

Imveliso Ikhowudi	Ilinganisiwe Ubungakanani (µm)	Ubungakanani	Isalathisi
			Ii-Hypervascular Tumors/ I-Arteriovenous Iimpazamo	I-Fibroid yesibeleko
U107S103	100-300	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	No
U107S305	300-500	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	No
U107S507	500-700	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
U107S709	700-900	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
U107S912	900-1200	Ii-microspheres ze-1ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
U207S103	100-300	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	No
U207S305	300-500	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	No
U207S507	500-700	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
U207S709	700-900	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe
U207S912	900-1200	Ii-microspheres ze-2ml: 7ml 0.9% i-sodium chloride	Ewe	Ewe