Isixhobo sokuQinisekisa iMithambo sePolyvinyl Alcohol Embolic Microspheres

Iimpawu zokusetyenziswa (Chaza)

IiMicrospheres ze-Emboliczenzelwe ukusetyenziselwa ukuthintela ukungasebenzi kakuhle kwemithambo yegazi (ii-AVM) kunye neethumba ezine-hypervascular tumors, kuquka nee-uterine fibroids.

Igama Eliqhelekileyo okanye Eliqhelekileyo:IiMicrospheres zePolyvinyl Alcohol EmbolicUlwahlulo

Igama:Isixhobo sokuQinisekisa iMithambo

Udidi: Iklasi yesiBini

Iphaneli:Intliziyo kunye nemithambo yegazi

Inkcazo yesixhobo

Ii-Embolic Microspheres zii-hydrogel microspheres ezinokucinezelwa ezinemilo eqhelekileyo, umphezulu ogudileyo, kunye nobukhulu obulinganisiweyo, ezenziwe ngenxa yokuguqulwa kweekhemikhali kwizinto ze-polyvinyl alcohol (PVA). Ii-Embolic Microspheres zenziwe yi-macromer ethathwe kwi-polyvinyl alcohol (PVA), kwaye ziyakwazi ukufudumala emanzini, azikwazi ukuxutywa, kwaye zifumaneka ngobukhulu obahlukeneyo. Isisombululo sokugcina sisisombululo se-sodium chloride esingu-0.9%. Umxholo wamanzi we-microsphere e-polymerized ngokupheleleyo yi-91% ~ 94%. Ii-Microspheres zinokunyamezela ukucinezelwa kwe-30%.

Ii-Embolic Microspheres zifumaneka zingenazintsholongwane kwaye zipakishwe kwiibhotile zeglasi ezivaliweyo.

Ii-Embolic Microspheres zenzelwe ukusetyenziselwa ukuqinisa imithambo yegazi emithanjeni (ii-AVM) kunye nee-hypervascular tumors, kuquka nee-uterine fibroids. Ngokuthintela ukuhanjiswa kwegazi kwindawo ekujoliswe kuyo, ithumba okanye i-malformation ayifumani izondlo kwaye iyancipha ngobukhulu.

Ii-Embolic Microspheres zinokuziswa ngee-microcatheters eziqhelekileyo kuluhlu lwe-1.7-4 Fr. Ngexesha lokusetyenziswa, ii-Embolic Microspheres zixutywa ne-arhente yokungafani engekhoyo ionic ukwenza isisombululo sokuxhoma. Ii-Embolic Microspheres zenzelwe ukusetyenziswa kube kanye kwaye zinikezelwa zingenazintsholongwane kwaye azina-pyrogenic. Ulwakhiwo lwesixhobo se-Embolic Microsphere luchazwe kwiTheyibhile 1 kunye neTheyibhile 2 ngezantsi.

Phakathi kobukhulu obahlukeneyo be-Embolic Microspheres, ubukhulu obunokusetyenziswa kwi-uterine fibroid embolization yi-500-700μm, 700-900μm kunye ne-900-1200μm.

Table: Uqwalaselo lwesixhobo se-Embolic Microspheres

Iisibonakaliso

Proumbhobho

Ikhowudi

Ilinganisiwe

Ubungakanani (µm)

Quantity

HyIi-Tumors ze-pervascular/ I-Arteriovenous

Maulwakhiwo

I-Fibroid yesibeleko

B107S103 100-300

Ii-microspheres ze-1ml: 7ml 0.9%

i-sodium chloride

Ewe Hayi

B107S305 300-500

Ii-microspheres ze-1ml: 7ml 0.9%

i-sodium chloride

Ewe Hayi

B107S507 500-700

Ii-microspheres ze-1ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe

B107S709 700-900

Ii-microspheres ze-1ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe

B107S912 900-1200

Ii-microspheres ze-1ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe

B207S103 100-300

Ii-microspheres ze-2ml: 7ml 0.9%

i-sodium chloride

Ewe Hayi

B207S305 300-500

Ii-microspheres ze-2ml: 7ml 0.9%

i-sodium chloride

Ewe Hayi

B207S507 500-700

Ii-microspheres ze-2ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe

B207S709 700-900

Ii-microspheres ze-2ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe

B207S912 900-1200

Ii-microspheres ze-2ml: 7ml 0.9%

i-sodium chloride

Ewe Ewe